The transition from the unipolar system to a multipolar one is generating tensions in two particular areas of the Eurasian landmass: the Mediterranean and Central Asia. The process of consolidation of polycentrism seems to be undergoing an impasse caused by the “regionalist” behavior adopted by the Eurasian powers. The identification of a single great Mediterranean-Central Asian space, functioning as the hinge of the Euro-Afro-Asian landmass, could provide operational elements for Eurasian integration.